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Prochlorperazine Maleate (Capazine) 是一种吩噻嗪类抗精神病药,主要用于治疗恶心、呕吐和眩晕。它比氯丙嗪更容易引起锥体外系疾病。
Prochlorperazine Maleate (Capazine) 是一种吩噻嗪类抗精神病药,主要用于治疗恶心、呕吐和眩晕。它比氯丙嗪更容易引起锥体外系疾病。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
25 mg | ¥ 198 | 现货 | |
50 mg | ¥ 356 | 现货 | |
100 mg | ¥ 640 | 现货 | |
200 mg | ¥ 987 | 现货 | |
500 mg | ¥ 1,980 | 现货 | |
1 mL x 10 mM (in DMSO) | ¥ 160 | 现货 |
产品描述 | Prochlorperazine Maleate (Capazine) is a phenothiazine antipsychotic used principally in the treatment of NAUSEA; VOMITING; and VERTIGO. It is more likely than CHLORPROMAZINE to cause EXTRAPYRAMIDAL DISORDERS. |
体外活性 | Prochlorperazine 通过下调cyclin E2表达抑制对他莫昔芬(tamoxifen)有抗性的MCF-7细胞的增殖。Prochlorperazine 具有影响雌激素受体(estrogen receptor, ER)功能的潜力,且可能改变内分泌治疗的反应[2]。 |
体内活性 | Prochlorperazine 在小鼠中可以诱导抗痛觉效应。经Prochlorperazine处理后的小鼠在转棒试验中显示出完整的运动协调能力,保持了正常的自发移动性和通过孔板测试显示的探索行为。[1]。 |
细胞实验 | Cells are treated 5 μM of prochlorperazine for 5 days and cell proliferation is measured by methylene blue staining or for 2 days and cyclin E2 mRNA levels are measured by qPCR.(Only for Reference) |
别名 | Prochlorperazin, Capazine, Prochlorperazine dimaleate salt, Stemetil, Compazine, 丙氯拉嗪 |
分子量 | 606.09 |
分子式 | C28H32ClN3O8S |
CAS No. | 84-02-6 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
溶解度信息 | H2O: < 1 mg/mL (insoluble or slightly soluble) Ethanol: 2 mg/mL (3.3 mM), Heating is recommended. DMSO: 45 mg/mL (74.25 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
溶液配制表 | ||||||||||||||||||||||||||||||||||||
Ethanol/DMSO
DMSO
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